Process Safety Assessment Platform

In the field of drug R&D, ensuring the safety of chemical processes is essential to prevent potential hazards and risks. A comprehensive chemical process safety assessment platform can provide valuable insights into the safety of the reagents and reactions used in drug R&D processes. We have established a laboratory research platform dedicated to the assessment of chemical process safety, providing customized, precise and reliable testing data and safety evaluations for our clients. This platform is outfitted with various cutting-edge equipment analytical instruments, which can evaluate the safety risks associated with chemical reactions and provides insights to mitigate these risks effectively.

Equipment at Our Platform

Our platform is equipped with state-of-the-art differential scanning calorimeter, automatic reaction calorimeter and accelerating rate calorimeter to conduct chemical processes safety assessments.

Differential Scanning Calorimeter (DSC): DSC is used to analyze the heat flow of a sample under controlled temperature conditions. This helps in identifying any exothermic or endothermic reactions that may pose safety risks during the drug R&D process.

Accelerating Rate Calorimeter (ARC): ARC is used to measure the heat released or absorbed during a chemical reaction under adiabatic conditions. This equipment is essential for evaluating the thermal stability of reagents and reactions to prevent potential hazards.

Automated Reaction Calorimeter: Automated reaction calorimeter allows for real-time monitoring of reaction heat and temperature. This equipment provides valuable data on reaction kinetics and heat generation, helping in the assessment of safety risks associated with chemical reactions.

Services Provided

Through the utilization of advanced equipment, our chemical process safety assessment platform offers a comprehensive range of services, including:

The main contents of these services are:

• Assessment of Reagents Used In The Reaction Process: Utilizing DSC and ARC, we conduct thermal stability testing on chemicals such as raw materials,  intermediates, catalysts, by-products, wastes, and all related materials involved in the separation process such as distillation and fractionation. By determining parameters such as initial decomposition temperature, decomposition enthalpy, specific heat, and TD24 (the temperature corresponding to the maximum reaction rate in an out-of-control system within 24 hours), we provide valuable insights into the thermal behavior of the substances involved.
• Chemical Reaction Safety Risk Assessment: Using our reaction calorimetry equipment, we can perform reaction calorimetry experiments to measure reaction heat, adiabatic temperature rise (ΔTad), and maximum temperature of self-reaction (MTSR). Through these thermodynamic and kinetic studies, we delve deep into the understanding of the chemical reaction processes, allowing us to assess and quantify potential risks accurately.
• Comprehensive assessment of Safety risks: By integrating the data obtained from the above experiments and analyses, we conduct a thorough assessment of the safety risks involved in the chemical processes. This evaluation includes decomposition enthalpy assessment, severity assessment of uncontrolled reactions, likelihood assessment of uncontrolled reactions occurrence, risk matrix evaluation, and classification of reaction process hazard levels.

How Can Our Platform Help You

Integration into Hazard and Operability Analysis (HAZOP) Studies

The data and results generated from our assessments can be seamlessly incorporated into HAZOP studies for in-depth risk analysis. By identifying potential hazards and operational vulnerabilities, organizations can strengthen their safety protocols and improve process efficiency.

Enhancing Piping and Instrumentation Diagrams (P&ID)

Our platform supports the refinement of P&IDs by providing essential data on reagent properties and reaction risks. This facilitates the development of accurate and reliable process diagrams, enhancing operational transparency and safety.

Improving Safety Control Measures

Established fine chemical and pharmaceutical companies enterprises can leverage our platform to refine safety control measures based on assessment results. This includes timely reviewing and updating safety operating procedures to align with the latest safety standards and best practices.

Developing Emergency Response Plans

Organizations can utilize the assessment outcomes to create specialized emergency response plans and on-site emergency handling procedures. Regular drills and simulations can be conducted to ensure preparedness and responsiveness in case of unforeseen incidents.

Our platform serves as a valuable resource for drug R&D and production companies looking to optimize their chemical processes and enhance their safety protocols. By leveraging our advanced equipment and expertise, we can assist you in identifying and mitigating safety risks, ultimately contributing to the success and efficiency of your drug development endeavors. Whether you require an in-depth evaluation of reagent stability, risk assessment of chemical reactions, or overall safety enhancement measures, our platform is dedicated to supporting your needs and ensuring the highest standards of safety and quality in your R&D processes. Contact us today to learn more about how our platform and services can benefit your projects.

It should be noted that our service is only used for research, not for clinical use.