Today, the complex process of drug discovery has become a competitive multidisciplinary field that encompasses chemistry, biology, pharmacy, and the intersections between them. Among them, bioorganic chemistry uses chemistry to deepen our understanding of biological processes, with a greater emphasis on molecular recognition and research related to drug action, biosynthesis problems, protein engineering, molecular evolution and others. This has important implications for drug research and development. To be successful in drug discovery, it is essential to have expertise in different fields. With years of experience in drug development and deep knowledge of bioorganic chemistry, our company is proud to offer high quality, fast and comprehensive bioorganic chemistry services at the most affordable prices in the industry, including design, synthesis, modification and research of various major types of biomolecules.
Our Services
Since its establishment, we have been proud to provide a full range of services to scientists in pharmaceutical companies and research institutions. In the regard of bioorganic chemistry service, we offer:
- Our chemical services team offers the design, synthesis, modification and research of the four major types of biomolecules which are most important in biochemical chemistry: nucleosides/nucleotides, carbohydrates, peptides and lipids. These biomolecules already offer breakthrough treatment opportunities for a variety of diseases. For example, synthetic oligosaccharides have potential as diagnostic markers and vaccines and several carbohydrates have been approved for the treatment of various diseases; Oligonucleotide have been developed for the treatment of a variety of genetic and rare diseases. The list goes on and on.
- In addition, we modify these biomolecules with various optimized modification and provide conjugated bodies of these biomolecules by cutting-edge chemical conjugation technology, to discover new functional molecules and facilitate drug development.
The details are as follows:
For nucleosides/nucleotides, our services include but are limited to:
- Synthesis of novel nucleosides/nucleotides, nucleoside amides, RNA oligonucleotide, siRNA oligonucleotide, microRNA oligonucleotide, antisense oligonucleotide, DNA oligonucleotide.
- Conjugation of oligonucleotides with peptides or proteins
- Perform complex oligonucleotide conjugation such as acid-amine coupling, alkyne-azide coupling, thiol-maleimide coupling, and S-S and C-S bond formation.
- Chemical labeling of nucleosides/nucleotides and their derivatives with biotin, fluorescent dyes, enzymes, or other specific molecules.
- Technical services for microspheres, nanoparticles and surface immobilization.
- Nucleoside/nucleotide analysis and bioactivity detection.
For carbohydrates, our services include but are limited to:
- Custom synthesis of carbohydrates products, including monosaccharide, oligosaccharide, nucleotide sugar, glycolipid, polysaccharide and carbohydrate antigen.
- Custom glycopeptide synthesis, custom glycoprotein synthesis and oligosaccharide library development.
- Modification and labeling of glycan such as fluorescence labeling, Biotinylation, PEGylation, isotope labeling, sulfate modification, phosphorylation modification, acetylation modification, etc.
- Custom conjugation services, including conjugation of carbohydrates to proteins, peptides, oligonucleotides, antibodies, drugs and other biomolecules.
- Carbohydrate analysis service.
- Bioactive carbohydrate screening service.
For peptides, our services include but are limited to:
- Custom peptide synthesis from crude to 99% purity, from mg to kg.
- Peptide modifications, including acetylation, dyes and fluorescent labeling, amidation, phosphorylation, isotope labeling, cyclization (disulfide bonds), CMK, spacers (PEGylation, Amino Hexanoic Acid), FMK, KLH or BSA Conjugations.
- Glycopeptide modifications such as Ser/Thr (GalNAc), Ser/Thr (GlcNAc), Ser/Thr (Gal-GalNAc), etc.
- Peptide and protein purification and structure analysis.
For lipids, our services include but are limited to:
- Design of complex lipid targets.
- Custom synthesis of lipid products from mg to hectogram grades, including anionic lipids, cationic lipids, neutral lipids, phospholipids, sphingolipids, ionizable lipids, pegylated lipids, fatty acid, mixed sterols, etc.
- Synthesis of various modified lipids such as PEGylated lipids, fluorescent lipids, biotinated lipids, halogenated lipids, oxidized lipids, phase-transition lipids, etc.
- Synthesis of lipid nanoparticle formulation.
- Lipid purification and analysis.
Why Choose Us?
Reliability
You will receive professional services from experts with extensive knowledge in medicine and biochemistry.
Innovation
We are constantly learning to explore and find innovative and cutting-edge ways to help you achieve better results.
Abilities
We provide a wide range of services to meet all aspects of your project needs.
Tailor-made Services
Your requirements are ours. We will design a unique solution for each customer.
We aim to provide professional bioorganic chemistry solutions to customers worldwide. If you are interested in our service, please feel free to contact us.
Related Services
It should be noted that our service is only used for research, not for clinical use.
