In several scientific disciplines, such as the characterization of recombinant proteins and the nutritional assessment of food proteins, quantitative amino acid analysis is a crucial technique. For targeting metabolites of interest, targeted metabolomics can extract data such as transitions and retention periods of standards. By gathering metabolic data from biological samples, one may assess metabolites' absolute qualitative levels.
Our company uses targeted metabolomics to provide professional amino acid quantitative analysis services to help customers identify significantly changed amino acids and their derivatives to further explore the pathogenesis of the disease, or analyze differential metabolites to find disease markers.
Service Overview
Our company has developed world-class expertise in amino acid detection and is aware of the crucial function amino acids play in physiological processes. Services focus on specific amino acids and their metabolic pathways and can be used to track biomarkers and enhance biological understanding in preclinical and clinical research.
Based on the cutting-edge GC-MS/MS technology platform, Our company has established a standard database of various amino acid metabolites, complete detection indicators, full coverage of important amino acid types, can achieve absolute qualitative and quantitative determination, and provides 19 standard curves for various substances. (Wide linear range: 5-500 ng/mL. Correlation coefficient: >0.99. It can meet the quantitative analysis of different types of complex samples.) We have a strict manual verification process to ensure the accuracy and reliability of the method.
Specific Service Content
- Identification of amino acid metabolic pathways.
- Identification of differential amino acids and their derivatives.
- Full Spectrum Amino Acid Analysis.
- Correlation analysis of amino acid biosynthetic gene expression and synthetic pathway metabolites.
Research Capabilities
Our company provides quantitative analysis to help you achieve your biomarker validation goals using precise and well-validated methods. Our targeted assays cover thousands of metabolites and lipids, spanning a wide range of biochemical classes, metabolic pathways, and physiological processes.
Our amino acid targeted research capabilities include, but are not limited to:
| Metabolite | Plasma/Serum (µg/mL) |
| Alanine | 1.00 |
| Arginine | 1.00 |
| Asparagine | 0.250 |
| Aspartic Acid | 0.250 |
| Proline | 1.00 |
| Serine | 0.400 |
| Threonine | 0.500 |
| Tryptophan | 0.500 |
| Tyrosine | 1.00 |
| Valine | 1.00 |
| Trans-4-hydroxyproline | 0.0500 |
| Glutamic Acid | 0.500 |
| Glutamine | 2.50 |
| Glycine | 0.750 |
| Histidine | 0.500 |
| Isoleucine | 0.250 |
| Leucine | 0.500 |
Sample Requirements
- Blood and bile: 10 µL
- Various tissues: 10 mg
- Feces: 10 mg
- For other sample types and dosages, please contact us.
- Analysis Method and Instrumentation: LC-MS/MS (Agilent 1290 UHPLC/Sciex QTrap 5500)
- Sample transportation: Dry ice volatilizes 3-4 kg a day. Please use enough dry ice for transportation (It is recommended to use large pieces of dry ice as much as possible, large pieces of dry ice volatilize slowly.).
Application
Our technology platform provides an ideal technology platform and high-quality testing services for amino acid analysis and research in the fields of biochemistry, food science, clinical medicine, feed science, and the chemical industry.
- Clinical oncology research
- Cardiovascular disease research
- Immune disease research
- Encephalopathy and liver disease research
- Neurological diseases research
- Food science, nutrition and developmental research
- Research in the fields of biochemistry, genetics, chemical engineering, etc.
If you are looking for smarter, higher quality solutions that incorporate best practices, please feel free to contact us.
Related Services
It should be noted that our service is only used for research, not for clinical use.
