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Continuous Flow Technology Platform

Continuous flow technology is a method of production that involves the constant movement of chemicals and pharmaceuticals through a manufacturing process without interruption. Continuous flow technology offers numerous advantages over traditional batch processes. It enables the integration of multiple reaction steps into a single system, reducing the need for complex purification and separation processes. In addition, continuous flow technology also has the advantages of high mass and heat transfer efficiency, intrinsic safety, good process repeatability, and continuous automated operation. Continuous flow technology is a globally recognized green path for pharmaceutical R&D and production.

Our continuous flow technology platform enables large-scale production of chemicals and pharmaceuticals. By leveraging the benefits of continuous flow technology, we are able to achieve higher throughput, shorter reaction times and improved product quality. At present, our continuous flow technology platform has completed the continuous flow process development of multiple innovative active pharmaceutical ingredient (API) projects and achieved commercial scale-up production.

Our Continuous Flow Technology Platform

Our continuous flow technology platform enables us to provide a range of services to support drug development and manufacturing processes. The main services include the following aspects:

Continuous flow process evaluation
Rapid screening of continuous flow process conditions
Seamless commercial scale-up of continuous flow processes
Design and application of continuous flow commercial equipment
Continuous flow process transfer
Continuous production of different APIs

Main Equipment For Small Trial

The success of continuous flow technology relies heavily on the quality of platform equipment utilized in the process. At our company, we have a wide range of cutting-edge equipment designed specifically for continuous flow applications.

Continuous flow multifunctional reaction platform

Applicable reaction types:

Nitrification reaction
Oxidation reaction
Grignard reaction
Curtius rearrangement reaction
Low temperature lithium reagent reaction
Gas-liquid and liquid-liquid heterogeneous reactions
.....

Continuous flow chemical reactor

Applicable reaction types::

Light-induced free radical reactions
Light rearrangement reaction
Photocyclization reaction
.....

Continuous flow fixed bed reactor

Applicable reaction types:

Nitro reduction reaction
Debenzylation reaction
Ester reduction reaction
Dehalogenation reaction
Reduction reaction of nitriles
Imine reduction reaction
Reduction reactions of alkenes and alkynes
Carbonylation reaction
.....

Continuous flow dynamic tubular reactor

Applicable reaction types:

Continuous flow solid-liquid two-phase reaction
Reaction with viscous reaction system
A reaction that produces a solid
.....

Production Equipments

Multifunctional production platform

Continuous flow pipe reactor

Platform Advantages

Increased efficiency. Continuous flow technology platform allows for continuous processing of materials, which means we can produce large quantities of chemicals or pharmaceuticals in less time. Compared with traditional batch processing methods, continuous flow technology can increase productivity and throughput.
Cost savings. By optimizing process efficiency and reducing waste, our continuous flow technology platform helps minimize production costs and improve overall profitability. In addition, the streamlined workflow can save potential costs such as labor.
Strict quality control. Our continuous flow technology platform provides better control over the production process by monitoring and adjusting variables in real-time, which reduces variability and provides greater control over key process parameters, resulting in increased consistency and reproducibility of the final product.
Scalability. Our platform also allows for seamless transition from small-scale production to large-scale production without the need for significant equipment or infrastructure changes.

It should be noted that our service is only used for research, not for clinical use.

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