Introduction
Cephalosporins are a class of β-lactam antibiotics that are widely used in the medical field for treating bacterial infections. They mainly work by inhibiting the synthesis of the bacterial cell wall. Specifically, they target the enzymes called penicillin-binding proteins (PBPs), which are essential for the cross-linking of peptidoglycan chains in the cell wall. By binding to PBPs, cephalosporins prevent the formation of a stable cell wall, leading to the lysis and death of the bacterial cell. Since the discovery of the first cephalosporin in 1945, new structures of cephalosporins have been continuously developed. Today, there are five generations of cephalosporins. First-generation cephalosporins are effective against gram-positive bacteria, while later generations have broader spectra and increased activity against gram-negative bacteria. As a leading provider of research chemicals and biochemicals, we have been instrumental in the development and production of cephalosporins for many years. At present, we offer a wide range of cephalosporins products.
Our Cephalosporin Series Products
*Products with other standards and packing specifications can be customized according to customer's needs.
Types of Cephalosporins
There are several different generations of cephalosporins, each with its own spectrum of activity and effectiveness against certain types of bacteria. First-generation cephalosporins, such as cefazolin and cephalexin, are effective against gram-positive bacteria and some gram-negative bacteria. They are often used to treat skin and soft tissue infections, as well as urinary tract infections. Second-generation cephalosporins, such as cefoxitin and cefuroxime, have increased activity against gram-negative bacteria and are more effective against some gram-positive bacteria than first-generation. Third-generation cephalosporins, such as ceftriaxone and cefotaxime, have an even broader spectrum of activity and are effective against both gram-negative and gram-positive bacteria. Fourth-generation cephalosporins, like cefepime, have extended spectra of activity against both gram-negative and gram-positive bacteria, as well as pseudomonas aeruginosa. Fifth-generation cephalosporins are designed to combat multi-drug resistant bacteria.
Applications of Cephalosporins
Cephalosporins are prescribed for a wide range of infections, including respiratory tract infections, urinary tract infections, skin and soft tissue infections, meningitis, pneumonia, bone infections, sinus infections, lung infections, biliary tract infections, bloodstream infections, ear infections, gonorrhea, sepsis, etc. In addition to treating common infections, cephalosporins are also used in surgical prophylaxis to prevent post-operative infections. This is especially important in procedures that involve implants or prosthetic devices, where the risk of infection is higher. Because of their low toxicity and high efficacy against common pathogens, cephalosporins are generally more popular than other antibiotics in these applications.
Our company is a global leader in the supply of high quality, pure and safe cephalosporin series products. Our comprehensive and competitive range of cephalosporin series products that stand up to various pharmaceutical applications. Moreover, we also provide custom synthesis services according to customer requirements. If you are interested in our products or have any questions or needs, please feel free to contact us. We will be happy to provide you with support and services.
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