Broad-spectrum metabolomics is a metabolomic assay technique that integrates the advantages of both non-targeted and targeted metabolite assays. Our company provides professional broad-spectrum metabolomic analysis services using a high-sensitivity UPLC-MS/MS liquid mass spectrometer and its own metabolite database, enabling high-throughput, sensitive, broad-coverage, and accurate metabolite detection.
Service Overview
Our company has a high-throughput sequencing technology platform and a standardized operational laboratory that it uses to deliver experimental protocols, address experimental issues, and evaluate experimental outcomes in accordance with partner needs. We use multiple reaction monitoring technology (MRM technology) for targeted detection and analysis of more than 200 substances, including nucleotides (60+), amino acids (60+), energy metabolism intermediates (30+), neurotransmitters (8+), vitamins (11+), biogenic amines (17+), and alkaloids (7+). The experimental cycle time is short and the quality is reliable.
Our comprehensive metabolome enables quantitative and qualitative detection of low-abundance trace-level chemicals, comparison of metabolite species and abundance differences between samples, screening of metabolites with substantial biological differences between groups. In addition, we have a professional bioinformatics team and supercomputer servers to provide comprehensive bioinformatics analysis services and technical support to our customers.
Technical Advantages
- High specificity and accuracy: MRM technology is more specific and accurate in analyzing target metabolites.
- High throughput: MRM technology can analyze 200 target metabolites at one time.
- Strict quality control: The most stringent quality control system is used to ensure the best qualitative and quantitative results for each item.
Technology Route
(1) Sample collection and processing
(2) Metabolite extraction
(3) Metabolite detection
(4) Data pre-processing and quality control
(5) Qualitative and quantitative metabolite analysis
(6) Multivariate statistical analysis
(7) Differential metabolite identification
(8) Metabolic pathway analysis
Data Analysis
| Table | Figure |
List of metabolite identification
Univariate statistical analysis
List of QC RSD calculation results (quality control) | Differential metabolite clustering analysis
List of differential metabolites |
Application Areas
- Basic medicine and clinical diagnosis: biomarkers, mechanisms of disease, disease typing, personalized treatment, etc.
- Biomedicine: drug mechanism of action, efficacy evaluation, drug development, etc.
- Microbiology: pathogenesis, drug resistance mechanisms, pathogen-host interaction research, etc.
- Bioenergy, environmental science: fermentation process optimization, biofuel production, environmental hazard risk assessment research, etc.
- Marine aquaculture: fishery resources, mariculture, fishery environment and aquatic product safety, etc.
- Food nutrition: food storage and processing conditions optimization, food components and quality identification, functional food development, food safety monitoring and testing, etc.
- Agriculture and forestry: mechanisms of stress resistance, growth and development mechanisms, breeding and conservation research, etc.
If you are looking for smarter, higher quality solutions that incorporate best practices, please feel free to contact us.
Related Services
It should be noted that our service is only used for research, not for clinical use.
