In drug formulation development, low-solubility drugs are increasingly available, and about 70% of new drug candidate compounds are insoluble. Our company has a professional technology platform for insoluble innovative drugs and a professional technology platform for high-end formulations, focusing on technology research services for high-end formulations.
Service Overview
Based on the morphological characteristics of the drug, combined with its physicochemical properties and stability, Our company conducts process studies to determine the initial preparation process of laboratory samples and establish the corresponding process control index. We address drug solubility and permeability with unique technologies to improve drug development success, shorten development time, and drive compounds to become truly valuable new drugs.
We have equipment and instruments commonly used for formulation processes and quality studies. Formulations include tablets, injectables, capsules, granules, ointments, creams, sprays, gels, syrups, tinctures, and oral liquid formulations.
In addition, we have the capability to develop new technologies such as extended-release formulations, nanoformulations, and fat emulsions.
Below is our formulation technology support.
- Micronization by airflow grinding
- Hot melt extrusion
- Liquid capsule filling
- Preparation of solid dispersion by spray drying
- Granulating after nano-suspension or micro-suspension
Research Capabilities
Our company has accumulated many years of experience in the research and application of innovative and generic drugs, and is still evolving and growing with time.
| Generic Drug Development and Strategy | Innovative Drug Development and Strategy |
- RLD selection, RLD comprehensive analysis
- Development of analytical methods
- Screening of key excipients
- Contrast with RLD key quality index to determine the prescription
- Optimization of production process parameters based on QbD
- Packaging materials and container screening
- Process scale-up and technology transfer
- Validation of analytical methods
- Development of quality standards
- Product stability investigation
| - Suspension (micro-suspension and nanosuspension)
- Active pharmaceutical ingredient bottling
- Micro-filling of active pharmaceutical ingredients
- Dry mixing and potting
- Liquid capsule filling technology
- Spray drying technology
- Dry/wet granulation and capsule filling/tableting
- Direct compression
- Pouch filling
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Overall Solutions
| Project Name | Formulation Technology Research Service |
| Technical Services | - Filled capsules with sustained- or delayed-release pellets
Delayed release micro-pills, granules, and small tablets are used to make hollow capsules to achieve delayed release in vivo. - Microsphere preparation technology
The drug is dissolved or dispersed in polymeric materials and then formed into skeletal microscopic spherical entities with a diameter of 1~25 μm by solvent volatilization method, which has a slow release effect. - Microcapsule preparation technology
Natural or synthetic polymer materials are used to wrap the drug into a drug library structure, and capsule materials with slow-release properties are used to make the drug release slowly. Using film dispersion, reverse-phase evaporation, etc., the drug is wrapped in a vesicle composed of lipid bilayers. |
| Deliverables | Original images and raw data.
A complete experimental report, including experimental materials, experimental procedures, and experimental results. |
| Cycle | Decide according to your needs. |
If you want to know more about service details, please feel free to contact us.
Related Services
It should be noted that our service is only used for research, not for clinical use.
