Our company works closely with our customers to provide fast translational and high quality cell screening data to save valuable resources and time. Our cell screening platform is designed to make better decisions early in the drug development process. We have experienced biologists dedicated to providing the best cell level screening services at the highest quality and lowest cost.
Service Overview
Cellular level screening is a drug screening model that more closely resembles physiological conditions. The model is developed to pinpoint cells where drugs will act. The desired cells are obtained using cell culture procedures, then biochemical level screening is utilized to determine how these cells interact with the prospective drugs. Cell-based drug screening is a large-scale systems biology approach that enables the measurement and evaluation of compound actions in living cells in order to identify potential medications.
Our company is aware of the necessity to speed up decision-making for the medication development process in order to make it more effective. To ascertain the biological activity and target binding affinity of compounds, we employ a number of cutting-edge biochemical, biophysical, and cell biological methods. These tools include screening modeling and method development, as well as molecular and cellular level compound screening.
Research Capabilities
Our company has the capability to perform cellular level drug screening modeling and drug screening.
1) Establishment of stable transitional cell lines.
2) Cellular level drug screening modeling.
a. GPCR-based reporter gene methods, calcium flow assays, cAMP assays, etc. Our company has 57 in-house established GPCR cell lines available.
b. Nuclear receptor-based reporter gene methods.
c. FACS-based assays, including cell cycle, apoptosis, etc.
d. Our company has a wide range of cancer cells available for testing in cell proliferation assays (96-well/384-well).
Overall Solutions
Our company's team of scientists has successfully completed hundreds of projects for leading pharmaceutical and biotechnology companies, including target validation, drug activity mechanisms, developmental assays, high-throughput drug screening, and services for experimental drug screening and biomarker development.
We offer a variety of cellular analysis platforms and tools to determine the biological function of each target and the results of pharmacological interactions to help decide whether to proceed with development.
| Project Name | Cellular Level Screening Service |
| Service Details | - Target verification experiment
- Adhesion, migration and invasion experiments
- Angiogenesis experiment
- Apoptosis experiment
- ADCC and CDC analysis
- Cell cycle analysis
- Pharmacokinetics, drug metabolism analysis
- High-throughput cytotoxicity screening
- In vitro combined drug experiment
- 3D clonogenic assays
|
| Deliverables | Original images and raw data.
A complete experimental report, including experimental materials, experimental procedures, and experimental results. |
| Cycle | Decide according to your needs. |
Our company's laboratory has a highly efficient platform for real-time quantitative analysis of live cells and a microplate counter for multi-parameter phenotypic screening. The laboratory is equipped with automated pipetting systems and advanced assay instruments to meet a variety of testing needs. With these high-content, high-throughput drug screening technologies, we can provide high-quality cellular analysis services.
For more information, please feel free to contact us.
Related Services
It should be noted that our service is only used for research, not for clinical use.
