The treatment of cancer and immune-inflammatory diseases is being revolutionized by biologics. In recent years, as innovative technological approaches have advanced, biologics consisting of monoclonal antibodies, fusion proteins, vaccines, cells, and gene therapies have been created. These biologics have been used in the treatment of disease. As a leader in the field of biological drug discovery, Our company now provides biological drug development services to our customers.
We have built a biopharmaceutical development team with extensive industry experience and state-of-the-art equipment. We can provide one-stop services such as stable cell line construction, process development, formulation studies, quality studies and quality standards, analytical method development and validation, stability studies, and clinical approval applications. We can help our customers shorten the time to clinical entry and significantly reduce their biological drug development costs.
Service Overview
In contrast to chemically synthesized small molecules with known structures, biologics are large molecules with complex, heterogeneous structures that are often unstable and sensitive to external conditions. Due to the complexity of these drugs, the development of biological drugs requires comprehensive and specialized knowledge. Our company's biology department has extensive experience in molecular biology, cell biology, in vitro biology, and structural biology.
From initial cDNA library construction to drug design through protein purification, structure determination, and analysis, we offer a full suite of biological services. In addition, we offer a broad portfolio of functional bioassays, immunoassays, and protein characterization tools to accelerate our customers' biological drug discovery and development.
Research Capabilities
Our research capabilities include, but are not limited to, the following.
GPCRs Drug Development and Screening
The biggest class of molecular target proteins with therapeutic potential belongs to the GPCR superfamily, which has 600 - 1000 proteins. Over 50% of all medications now on the market work by activating GPCRs, and GPCRs are currently the focus of 40% of drug screenings. GPCRs are now the main focus of pharmacological screening. Our company offers expert medication development and screening services for GPCRs.
Ion Channel Drug Development and Screening
Ion channels are transmembrane proteins that are found on cell membranes and are encoded by genes. They serve as the membrane's route for the passive transport of different inorganic ions. Ion channel diseases are a group of illnesses where structural changes and malfunctioning of ion channels are brought on by medication interactions or gene mutations. The third main focus of drug screening in recent years has also drawn more attention: the development of drugs that target ion channels. Our company offers services for ion channel medication development and screening.
Enzyme and Membrane Transporter Protein Drug Development and Screening
More than 500 proteins are hypothetically expected to be potential kinases out of thousands of protein libraries. Protein kinases have emerged as the second-most significant drug screening target among known therapeutic targets in the field of drug screening. You can get medication development and screening services for enzymes and membrane transporter proteins from Our company.
Overall Solutions
| Project Name | Biological Drug Development Service |
| Service Details | - Modeling of key drug targets based on cancer cell signaling pathway analysis and high-throughput screening of new drugs
- Genetic improvement and biosynthetic pathway studies of key secondary metabolites of microorganisms based on systems biology and systems biotechnology
- Fermentation regulation of important microbial secondary metabolites based on metabolomics and real-time metabolic flow analysis
- Construction, quality analysis and control of important biotechnological drugs based on genetic engineering
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| Deliverables | Within agreed time, we will provide the summary to experiment data and conclusions, as well as a final experiment report. |
| Cycle | Decide according to your needs. |
For more information, please feel free to contact us.
It should be noted that our service is only used for research, not for clinical use.
