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Enzyme Catalysis Technology Platform

Enzyme catalysis technology plays a crucial role in the development of small molecule drugs. With enzyme catalysis technology, researchers can design and produce small molecule drugs with improved pharmacokinetic properties, potency, and reduced side effects. Enzyme-catalyzed processes also offer milder reaction conditions, high yields, and the ability to perform chemistries that are challenging using traditional chemical methods. In addition, enzyme catalysis technology allows for the development of more sustainable and cost-effective drug manufacturing processes, as enzymes can be reused multiple times without losing their catalytic activity. As the field of enzymatic drug synthesis continues to advance, we can expect to see more innovative and effective small molecule drugs being developed using this technology.

Our company has an advanced enzyme catalysis technology platform and can provide customers with services related to enzyme molecules and enzyme preparations. Our platform utilizes a range of enzymes that have been carefully selected and engineered to catalyze specific chemical reactions with precision and speed. This allows us to produce high-quality drugs in a more cost-effective and environmentally friendly manner, improving drug purity and yield, thereby accelerating drug discovery and development.

Our Enzyme Catalysis Technology Platform

We already have the equipment conditions and technical capabilities for custom development and molecular modification of enzymes, enzyme library screening, enzyme preparation, and enzyme catalytic process development, and can provide customers with services related to enzyme-catalyzed synthesis of drugs and intermediates.

Custom development services for enzymes. The required enzymes can be customized and developed according to the synthetic route of the project to catalyze the reaction.
Enzyme molecular modification services. We use directed evolution methods such as random mutation (such as error-prone PCR) and site-directed mutation to modify enzyme molecules to improve catalytic performance (selectivity and catalytic activity).
Enzyme library screening services. We have established an enzyme library with more than 400 enzymes of different types, including ketone reductase, aminotransferase, hydrolase, enene reductase, imine reductase, monoamine oxidase, etc. The number of enzymes in the enzyme library will continue to increase and can be used for screening applications in different types of projects.
Enzyme preparation services. We can develop and optimize enzyme preparation processes and prepare different enzyme preparations including enzyme liquid, enzyme powder and immobilized enzyme on demand. Our laboratory can prepare kilogram-level enzyme liquid and hundreds of gram-level enzyme powder, and the enzyme preparation factory can prepare ton-level enzyme liquid and hundreds of kilogram-level enzyme powder.
Enzyme catalytic process development services. We can develop enzyme catalytic processes and perform process optimization and scale-up.

Main Laboratory Equipment

PCR instrument
Electrophoresis instrument
Biological microscope
Ultra-trace spectrophotometer
Full-wavelength microplate reader
Large-capacity constant temperature shaker
Biochemical incubator
Gel imager
UV-visible spectrophotometer
Electric automatic steam sterilization pot
Ultrasound crusher

Ultra-low temperature refrigerator
Moisture meter
Automatic polarimeter
High-pressure homogenizer
High-speed refrigerated centrifuge
Freeze dryer
Ceramic membrane
Microplate constant temperature oscillator
10-50L double fermentation tank system
5L-10L double enzyme reaction glass kettle
...

Production Equipment

5-Ton tank fermentation system
Centrifuge
Homogenizer

Ceramic membrane
Freeze dryer
...

It should be noted that our service is only used for research, not for clinical use.

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