Physicochemical property testing is an integral part of drug and biological product validation, manufacturing support, and lot release planning. Our company provides early physical and chemical property screening services through our in vivo pharmacokinetic (PK) service to rapidly assess the pharmaceutical properties and safety of customers' new drugs.
Service Overview

Our company's early physical and chemical property screening is a personalized and customized innovative scientific research service. We use our drug metabolism and pharmacokinetics (DMPK) platform to select the most robust drug formulations and optimize drug discovery and preclinical development strategies. Available as an integrated drug discovery platform or as a stand-alone service, our services include advanced LC-MS/MS and HPLC technologies, as well as ELISA and MSD assays.
Covering a range of animal species and tissue types, our exceptional in vivo expertise and models can meet all your needs and inform your drug development. Through an extensive quality assurance system, we can ensure that every study receives high-quality data.
Research Capabilities
Our company requires a detailed evaluation of each project before determining the corresponding analysis plan and price. Our research capabilities include but are not limited to the following:
- In vivo PK study design
- In vivo PK profile analysis of small molecules and macromolecules
- Single, multiplayer, and combined PK research
- In vivo crossover study of bioavailability
- Plasma protein binding rate study
- PK tissue distribution and mass balance studies
- Fecal assay
Fig.1 Differential mobility spectroscopy can be used to probe slightly solvated forms of molecules, providing insight into their bulk physicochemical properties, including passive cell permeability. (Liu C, et al. 2017)
Overall Solutions
Project Name | Early Physical and Chemical Properties Screening |
Service Details | - Method development and validation
- Dosing regimen analysis
- Quantitative analysis (parent compound, metabolite)
- Analysis of various biological samples (blood, plasma, bile, urine, feces, tumor tissue, etc)
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Deliverables | Within agreed time, we will provide the summary to experiment data and conclusions, as well as a final experiment report. |
Cycle | Decide according to your needs. |
For more information, please feel free to contact us.
Reference
- Liu C, et al. (2017). "Assessing Physicochemical Properties of Drug Molecules via Microsolvation Measurements with Differential Mobility Spectrometry." ACS Cent. Sci. 3(2): 101-109.
Related Services
It should be noted that our service is only used for research, not for clinical use.