Metabolomics is a study method that mimics the research ideas of genomics and proteomics to quantitatively analyze all metabolites in an organism and discover the relative relationship between metabolites and physiological and pathological changes.
Our company offers customers expert delivery of metabolomics services, including targeted metabolomics services, untargeted metabolomics services, and unknown metabolite identification services, by combining cutting-edge analytical assays with computational analysis methods like pattern recognition and expert systems.
Service Overview
Metabolites are small molecules that are substrates/intermediates/products of cellular metabolic processes, and their changes reveal the function of genes more directly. Metabolic profiling can systematically identify and quantify metabolites at specific time points in biological samples, and can instantaneously reflect the physiological state of cells, and the activity and status of tissues. For metabolomics services, we have specialized mass spectrometry equipment that includes analytical techniques for analyzing and quantifying metabolites in various sample types.
Also, we offer professional advice and assistance with sample preparation and data analysis. Cellular/tissue digest, serum/plasma, saliva/sweat, urine/feces, gastrointestinal fluids, exhaled breath, etc., are typical samples used in metabolomics research. To extract the necessary metabolites from each sample, a unique extraction and purification process is needed.
Research Capabilities
Non-targeted Metabolomics Studies
Non-targeted metabolomics' main ideas are to compare experimental and control groups, identify every metabolite present in a sample, gather quantitative data, and screen for biologically significant metabolites that differ between groups.
Our company's non-targeted metabolomics studies usually use two detection techniques: gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-mass spectrometry (LC-MS).
- GC-MS untargeted metabolomics assays
GC-MS is one of the mature chromatography-mass spectrometry techniques. Due to its high resolution, high sensitivity, good reproducibility, a large number of standard metabolite libraries, and relatively low cost, it is suitable for the analysis of metabolites with low relative molecular masses (within 500 Da), low polarity, and low polarity. Boiling point.
- LC-MS untargeted metabolome assays
LC-MS untargeted metabolomic technology utilizes the LC-MS platform for qualitative analysis and quantitative detection of all metabolic components in a specific biological sample under limited conditions.
Non-targeted metabolomics research services specifically include:
- Plant metabolomics
- Microbial metabolomics
- Serum metabolomics
- Urine metabolomics
- Body fluid metabolomics
Targeted Metabolomics Studies
Targeted metabolomics is an important part of metabolomics research and an extension of total metabolomics research. Compared with total metabolomic analysis, targeted metabolomic analysis has several characteristics such as high specificity, high detection sensitivity and accurate quantification.
Targeted metabolomics research services specifically include:
- Metabolic flux analysis
- Fatty acid testing
- Lipid metabolism detection
- Detection of glucose metabolism
- Purine metabolism detection
- Pharmacokinetic research
- Disease biomarker testing services
- Research on drug targets and mechanism of action, etc.
Unknown Metabolite Identification
To identify unknown metabolites, we have advanced instrumentation that provides accurate information such as retention times, mass spectra, determination of molecular masses and elemental composition of compounds. Combining this information with various algorithms, we can identify compounds.
Overall Solutions
| Project Name | Metabolomics Services |
| Service Options | |
| Deliverables | Original images and raw data.
A complete experimental report, including experimental materials, experimental procedures, and experimental results. |
| Cycle | Decide according to your needs. |
If you are looking for smarter, higher quality solutions that incorporate best practices, please feel free to contact us.
Related Services
It should be noted that our service is only used for research, not for clinical use.
