The purpose of genomics is to collectively characterize and quantify all genes in an organism and to study the relationships among them and their effects on the organism. Genome sequencing and analysis is another aspect of genomics, which combines bioinformatics and high-throughput DNA sequencing to put together and examine the structure and function of complete genomes.
Our company provides a knowledgeable and wide range of genetic services to its customers. We will support biomarker discovery and mechanism of action identification as your dependable partner to promote diagnostic development and international commercialization while ensuring that your project's schedule is adhered to.
Service Overview
Our company uses highly sensitive PCR, real-time PCR, NGS technology, and advanced data analysis to deliver high-quality, interpretable results. Our genomics services include nucleic acid extraction, sequencing, bioinformatics analysis, reporting, and visualization, and can be used as a stand-alone service or as part of a comprehensive preclinical program.
We accept a variety of RUO sample types, including fresh and frozen cells and tissues, FFPE, biopsies, and oral swabs. A summary of experimental data and findings, as well as a final lab report, will be provided within an agreed-upon timeframe. The experimental period is determined by the customer's needs.
Customers can customize their analysis and use our standard genomics services, including
- Single gene and pathway gene expression
- Viral copy number
- Gene mutation
- Gene fusion validation
- SNP genotyping
- Differential and tissue-specific gene expression
- Functional annotation of differentially expressed genes
- Pathway and network analysis of differentially expressed genes
Research Capabilities
Through our highly flexible and customizable platform and our long experience in analyzing preclinical research samples, Our company can meet all your genomics research needs.
- We streamline preclinical workflows by integrating genomics services into existing in vitro or in vivo studies.
- We use state-of-the-art platforms to meet your sequencing needs from short read length to long read length sequencing and structural variant detection.
- We explore and validate drug mechanisms through advanced genomic analysis.
- We use genomic analysis of preclinical samples to identify genomic features associated with drug response.
- We understand drug resistance through immunogenomics of tumor immune interactions.
- We use our proprietary tools and model data, including our large database of NGS characterization models and algorithms, to discover biomarkers using NGS data.
Targeted Gene Sequencing Service
Our company specializes in targeting key gene sets by performing high-depth sequencing of targeted genes using finished or custom gene sets. Amplicon sequencing is a highly targeted method for analyzing genetic variation in specific genomic regions. ultra-deep sequencing of PCR products allows you to efficiently identify and characterize variants. Our amplicon technology uses a pair of oligonucleotide probes specifically designed to target and capture the target region, followed by next-generation sequencing (NGS).
Our company supports two targeted sequencing methods: targeted enrichment and amplicon methods.
- Targeted Enrichment: Biotin-labeled probes capture the target region during hybridization and are then separated by magnetic sedimentation. Depending on the experimental design, targeted enrichment methods can capture regions of 20 kb-62 Mb.
- Amplicon Sequencing: Target regions are amplified and purified using a highly specific oligonucleotide library. Amplicon sequencing methods allow researchers to sequence 26-1536 targets at a time, with a distribution range of 150-450 bp per target, depending on the library construction kit.
If you want to know more about service prices or technical details, please feel free to contact us.
Related Services
It should be noted that our service is only used for research, not for clinical use.
