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Fluorine Chemistry Technology Platform

Fluorine is one of the most reactive and electronegative elements in the periodic table and can significantly affect the physicochemical properties of molecules, making it a valuable tool for medicinal chemists. Introducing fluorine into drugs through fluorine chemistry technology can increase lipophilicity and metabolic stability, thereby improving the bioavailability and pharmacokinetic properties of the drug. In addition, fluorine chemistry technology can also be used to optimize drug candidates through structure-activity relationship studies. By systematically introducing fluorine substitutions into a series of related compounds, medicinal chemists can identify the optimal position and number of fluorine atoms for maximizing the desired pharmacological effects. Fluorine chemistry technology offers a versatile and powerful tool for drug discovery and development, enabling the design of more potent, selective, and bioavailable small molecule drugs.

Our company is focused on leveraging the unique properties of fluorine to develop innovative drug candidates with improved pharmacokinetic and pharmacodynamic properties. Our fluorine chemistry technology platform is at the forefront of drug discovery and development, enabling us to discover and develop a wide range of fluorine-containing compounds, from fluorine-containing small molecules to drugs. In addition, our expert team has extensive experience in designing and synthesizing fluorine-containing compounds and can provide customers with technical services related to drug synthesis. Our fluorine chemistry technology platform is dedicated to harnessing the unique properties of fluorine to promote the development of the biopharmaceutical field.

Our Fluorine Chemistry Technology Platform

Our fluorine chemistry technology platform enables us to provide the following services:

Design and synthesis of fluorine-containing small molecules for drug discovery and development.
Design and synthesis of fluorinated reagents and fluorinated building blocks for drug discovery and development.
Synthesis of fluorine-containing drugs and intermediates.
Medicinal chemistry optimization of lead compounds to enhance potency, selectivity, and pharmacokinetic properties.
Process development and scale-up of fluorine-containing compounds for preclinical and clinical studies.

Platform Advantages

One of the primary advantages of our fluorine chemistry technology platform is the ability to independently design and synthesize novel fluorinated reagents and fluorinated building blocks. The platform can also carry out experiments for screening the reactivity of parallel fluorinated reagents. In addition to providing customers with kilogram-level fluorinated reagents and fluorinated building blocks, it can also provide customers with services from the design of fluorinated reagents to the optimization of reactivity.
Second, our fluorine chemistry technology platform allows for precise control over the stereochemistry and conformation of drug molecules, which can significantly impact their pharmacological properties. This level of control enables us to design drugs with optimal efficacy and safety profiles. And we are able to fine-tune the properties of drug candidates by strategically introducing fluorine atoms into their structures. This can increase their metabolic stability, enhance their binding affinity to target proteins, and improve their overall therapeutic efficacy.
Third, our fluorine chemistry technology platform enables flexible production capacity from small volumes to commercial production. The controllable reaction temperature is in the range of -100 ℃ to 300 ℃, and the controllable reaction pressure is in the range of -0.1Mpa to 10Mpa. It can produce a variety of complex fluorine-containing compounds on a large scale.

It should be noted that our service is only used for research, not for clinical use.

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