Our company provides specialized flow cytometry services, providing complete flow cytometry services from experimental design through sample processing, acquisition and data analysis for all phases of drug development from exploratory studies to preclinical GLP and ultimately supporting clinical trials.
With the advantages of speed, precision, and accuracy, flow cytometry analysis produces extraordinarily rich data sets that show biological activities at single-cell resolution. We use state-of-the-art technology to deliver high quality, highly parametric data with little to no variability and ongoing efficiency measures to meet our customers' unique research needs. Currently, the use of flow cytometry to detect peripheral blood leukocytes, bone marrow cells and tumor cells is an important part of clinical testing.
Service Overview
Our company gains new insights into drug mechanisms and PD through powerful and in-depth immunophenotyping. Our flow cytometry services maximize the benefits of immunotherapy, limit unnecessary toxicity, and increase the chances of preclinical/clinical success by fully characterizing relevant cells.
We use a standardized process to track each sample from collection to analysis. In addition we can store liquid and solid biological specimens at controlled ambient temperatures, 4℃, -20℃, -80℃ and in liquid nitrogen.
Using our high quality flow cytometry data, customers can better understand.
- The immune composition of tumors, blood, spleen, lymph nodes, etc.
- The effect of treatment on the frequency and function of cell subpopulations.
- Individual sample variation and response heterogeneity.
Research Capabilities
Our company's flow cytometry services have capabilities that include, but are not limited to, the following.
- Immunophenotyping: Our experience ranges from standard immunophenotyping to flow cytometry analysis for the elucidation of intracellular markers.
- Receptor Occupancy: Flow cytometry can be a powerful tool for assessing receptor occupancy (RO) to evaluate therapeutic binding to target receptors. This can be assessed using direct or indirect methods.
- Functional Analysis: We have a complete cell culture service capability to demonstrate whether cells have the ability to perform certain functions. Currently, we have assays to assess natural killer cell function and basophil activation assays (BAT).
- PBMC Isolation: Some applications in flow cytometry may require isolation of peripheral blood mononuclear cells (PBMC). At FCSL, we can provide support for PBMC isolation as needed for your specific flow cytometry analysis.
Overall Solutions
| Project Name | Flow Cytometry Service |
| Service Details | We offer a full range of flow cytometry assays, including:- Cell analysis and subsetting: lymphocytes (TH, TC, TM, Treg and B cells), stem cells (LSC and HSC), reticulocytes, myeloid-derived suppressor cells (MDSC), macrophages and monocyte subsets
- Receptor occupancy (RO) measurement;
- Intracellular staining (ICS);
- Tetrameric flow cytometry for antigen-specific flow cytometry;
- Detection and quantification of rare cells based on phenotype, apoptosis or phosphorylation status;
- Cytokine measurement using cell counting bead assay;
- CAR-T cell characterization for cell therapy development;
- Fluorescence-activated cell sorting (FACS sorting and analysis).
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| Deliverables | Original images and raw data.
A complete experimental report, including experimental materials, experimental procedures, and experimental results. |
| Cycle | Decide according to your needs. |
For more information, please feel free to contact us.
Related Services
It should be noted that our service is only used for research, not for clinical use.
