General toxicology studies, which form the basis of safety assessment, are essential for proving the efficacy of commercially available pharmaceuticals. Our company offers general toxicity study services for GXP-compliant safety evaluation of pharmacological, veterinary, chemical, and device development.
Our broad expertise enables us to guide and carry out both conventional and cutting-edge toxicology study designs, as well as manage unexpected discoveries or toxicity problems throughout your project. Our seasoned multidisciplinary team's direction and insight help us make sure your project is current, applicable, and future-proof.
Service Overview
Our company conducts generic toxicological tests to evaluate the level and severity of an experimental substance's toxicity to animals. These studies' objectives are to identify any potential target organs or functions that may be impacted as well as to establish and assess the association between different dose levels delivered and undesirable effects. The pattern of toxic effects can also be identified, if possible.
Our company's general toxicology study services include acute toxicology studies, repeat dose toxicity studies, subchronic/chronic toxicity studies, and maximum tolerated dose studies.
- Our streamlined, well-designed acute toxicity studies can aid in the choice of dosages for preliminary repeat dose toxicity testing as well as in the prediction of potential target organ harm.
- The growth of your development program is supported by our preclinical toxicology studies experience through repeat dosage toxicity testing, guaranteeing that you get the trustworthy safety testing data you require.
- For the purposes of your preclinical drug development program, we can test your medicinal entity for any negative effects over a longer duration if it is intended for repeated or long-term usage in patients.
- We will assist you in establishing early safety by swiftly analyzing the toxicological profile of your new medicinal agent.
Research Capabilities
Acute and Dose Range Studies
The intrinsic toxicity of new test items is defined and characterized using acute single-dose toxicity testing. For the purpose of evaluating risk, picking the right dose level for a toxicity study is crucial. To help you decide whether to do long-term studies, our toxicologists can provide you with advice and plan dose-ranging research, such as dose escalation and maximum tolerated dose studies.
Subchronic and Chronic Studies
Subchronic and chronic toxicity investigations utilizing rodent and non-rodent models are frequently included in general toxicology programs. The oral (by gavage, pill, or incorporation into a lab-formulated diet), dermal, subcutaneous, intravenous, and intramuscular methods of administration are the most popular ones for GLP toxicology investigations, while we also provide many more specific routes and designs.
Carcinogenicity Studies
We perform carcinogenicity GLP toxicology studies in rodents in full compliance with GLP regulations. In addition, we offer the rasH2 model as an alternative to the full carcinogenicity protocol.
Overall Solutions
| Project Name | General Toxicology Study Services |
| Service Options | |
| Deliverables | Within agreed time, we will provide the summary to experiment data and conclusions, as well as a final experiment report. |
| Cycle | Decide according to your needs. |
For more information, please feel free to contact us.
Related Services
It should be noted that our service is only used for research, not for clinical use.
