The histopathological diagnostic analysis is thought to be a crucial factor in determining the existence and kind of the disease during the diagnostic procedure. Before the body displays overt clinical signs, histopathological analyses can reveal the impact of medications on the body's tissues and organs, serving as a guide for disease prevention and therapy.
Our company works closely with its clients to guarantee that the histopathology studies we do are of the highest caliber. We offer full preclinical histopathology solutions to these customers. We are able to satisfy our customer's expectations while offering them high-quality services because of our knowledge and competence.
Histopathology Studies
Our company has a highly experienced and skilled pathology team, equipped with advanced instrumentation and digital pathology diagnostic systems, robust pathology staining methods, and the ability to perform remote pathology diagnostic services. All experimental designs and operations comply with international GLP regulations to ensure accurate and reliable test results. We perform toxicity pathology evaluations using mice, rats, rabbits, dogs, and non-human primates.
Our histopathology laboratory skills include the following.
- Necropsy of small and large animals.
- In vitro organ perfusion fixation.
- Microdissection.
- High resolution gross anatomical photography.
- Various immunohistochemical tissue markers (lymphocyte sorting marker staining, tumor origin identification staining, circulating immune complex staining).
- Immunohistochemical staining (IHC).
- Immunofluorescence chemical staining (IF)
- Immunocytochemical staining (ICC)
- In situ hybridization (ISH).
- Fluorescence in situ hybridization (FISH).
- Routine hematoxylin-eosin (HE) staining.
- Various special stains.
1. Pigmentation classification marker staining (iron-containing haematoxylin, Prussian blue staining).
2. PAS staining (glycogen staining).
3. Masson trichrome staining (collagen fibril staining).
4. Congo red stain (amyloid stain).
5. Toluidine blue staining (mast cell staining, electron microscopic semi-thin section staining).
Histopathology Solutions
Our company offers a comprehensive solution in the histopathology section.
Experimental Pathology Evaluation
- We provide pathological diagnostics on a wide range of genera, including but not limited to rats, mice, guinea pigs, rabbits, dogs, non-human primates, and minipigs.
- Analysis of oncology studies such as biomarker screening, localization, density, CDX, tissue microarrays (TMA), and cell line microarrays (CMA) for cell lines.
- Inflammatory/immune disease models analysis, such as EAE models, IBD models, pulmonary fibrosis models, COPD models, and CIA models.
- Tissue and organ damage analysis, such as stroke, myocardial infarction (AMI), nephropathy, pain, central nervous system (CNS) diseases.
- Tissue and organ metabolic and degenerative disease analysis such as liver disease, skeletal muscle degeneration, bone degeneration, connective tissue degeneration, and others.
Toxicopathological Evaluation
We have extensive diagnostic experience with many types of toxicity study tests, including short-term toxicity tests, sub-chronic toxicity tests, chronic toxicity tests, and carcinogenicity studies. We provide non-GLP toxicology-pathology solutions, including gross and histopathology readings, analysis, evaluation, review and reporting.
If you are looking for the best solution for the safety evaluation of drugs for human use, please feel free to contact us.
It should be noted that our service is only used for research, not for clinical use.
