The problem of pesticide residues is pervasive, endangering human health and seriously contaminating food. The harm is not only in its general toxicity, but also in its reproductive toxicity and its carcinogenic, teratogenic and mutagenic effects on humans.
Our company provides specific toxicity testing services for pesticides to help reduce the harmful effects of pesticide residues on humans such as neurological effects, carcinogenic effects, liver effects, mutagenic effects, etc.
Pesticide Special Toxicity Test Overview
Carcinogenicity, teratogenicity, and mutagenicity of pesticides are all within the scope of their specific toxicity studies. Carcinogenicity and mutagenicity, carcinogens and mutagenicity are closely related. These toxicities are not easily detectable and require long latency periods or exposure under specific conditions.
Our company offers a wide range of specific toxicity testing services.
- Mutagenicity assay: The purpose is to test subjects for mutagenic effects and can also be used as a rapid screening test for carcinogens.
- Carcinogenicity test: Short-term carcinogenicity tests and long-term carcinogenicity tests.
- Teratogenicity test: The drug is administered to pregnant rats or rabbits during the organogenesis stage to observe the effects on the offspring.
- Reproductive developmental toxicity test: The potential toxicity of the test substance on germ cells, fertilization, pregnancy, delivery, lactation and other parental reproduction, as well as offspring embryo-embryo development and postnatal development.
Test Range
Organophosphorus insecticide, organophosphorus insecticide, diamide insecticide, neonicotinoid insecticide, carbamate pesticide, organic gas pesticide, benzoyl gland insecticide, pyrethroid pesticide, inorganic insecticide, biogenic insecticide, organic sulfur pesticide, pyrrole pesticide, fungicide, triazole fungicide, moringa fungicide, paclobutrazol, dimethoate, paraquat, quinclorac, isoxaflutole, gramophone, high-efficiency cover grass energy, plant growth regulator, etc.
Pesticide Safety Evaluation Solutions
The following are available from Our company's special toxicity testing service.
Mutagenesis Experiments
This is an in vitro mutagenesis assay using microorganisms. We test the ability of a test subject to induce a histidine nutrient-deficient mutant strain (his-) of Salmonella typhimurium to revert to a wild-type (his+) mutation.
For more information, please click Bacterial Revertant Mutation Test.
- Mammalian cell gene mutation assay
This is a genetic forward mutation assay for in vitro cultured cells. We evaluate the mutagenicity of the test and its intensity by testing the ability of the test to induce mutations in mammalian cells cultured in vitro.
For more information, please click In Vitro Mammalian Cell Gene Mutation Test.
- Chromosomal aberration assay
We directly observe the structural or numerical changes in the chromosomes of biological cells in response to a test substance. The test can be performed on somatic cells or germ cells.
- Bone marrow cell micronucleus test
The presence of micronuclei indicates that mutations in genetic material have occurred. We give subjects to test animals at a certain dose and number of times. The bone marrow is removed after slaughter. A microscopic examination is performed to determine the rate of micronuclei appearance.
For more information, please click In Vivo Mammalian Erythrocyte Micronucleus Test.
- Dominant lethal mutation test
This is a germ cell mutagenicity test used to detect genetic damage to overall mammalian germ cells by the subject.
For more information, please click Rodent Dominant Lethal Test.
Carcinogenicity Test (single administration): We administer different doses of a test substance to experimental animals through a certain route and observe the development of tumors over a near lifetime to assess the chemical carcinogenic effect of long-term exposure to the test substance on the animals.
Chronic Toxicity and Carcinogenicity Combination Test (repeated administration): We repeatedly administer the test substance to the animals for most of their life cycle and observe both chronic street effects and chemical carcinogenic effects on the experimental animals.
Teratogenicity Test
We use teratogenic tests to detect toxic effects such as embryonic death, structural malformation, and growth retardation. The test is commonly performed on sexually mature rats or mice.
For more information, please click Teratogenicity Test.
Reproductive Developmental Toxicity Test
We use mammals for reproductive toxicity testing. In addition, we usually use the same species and strains of animals as in other toxicology tests so that the results are comparable with other toxicology tests and may avoid excessive pre-testing.
Other Specific Toxicity Tests
If you are looking for the best solution in the field of pesticide toxicology research, please feel free to contact us.
Related Solutions
It should be noted that our service is only used for research, not for clinical use.
