| Catalog Number |
PR1169630403 |
| CAS |
1169630-40-3 |
| Description |
Used to directly couple with the fermented peptide intermediates for the synthesis of semaglutide, this product introduces crucial segments, including the 18-carbon fatty acid side chain, AEEA-AEEA, and glutamic acid, to confer a long-acting effect. It can effectively avoid racemization and degradations, increase yield, and improve product purity. This is achieved by removing the tert-butyl group before coupling, thus eliminating the need to remove this protection group via TFA. |
| Synonyms |
17-((S)-1-Carboxy-3-{2-[2-({2-[2-(2,5-dioxo-pyrrolidin-1-yloxycarbonylmethoxy)ethoxy]ethylcarbamoyl}methoxy)ethoxy]ethylcarbamoyl}propylcarbamoyl)-heptadecanoic acid |
| IUPAC Name |
18-[[(1S)-1-carboxy-4-[2-[2-[2-[2-[2-[2-(2,5-dioxopyrrolidin-1-yl)oxy-2-oxoethoxy]ethoxy]ethylamino]-2-oxoethoxy]ethoxy]ethylamino]-4-oxobutyl]amino]-18-oxooctadecanoic acid |
| Molecular Weight |
830.96 |
| Molecular Formula |
C39H66N4O15 |
| InChI |
InChI=1S/C39H66N4O15/c44-32(18-17-31(39(52)53)42-33(45)15-13-11-9-7-5-3-1-2-4-6-8-10-12-14-16-37(49)50)40-21-23-54-25-27-56-29-34(46)41-22-24-55-26-28-57-30-38(51)58-43-35(47)19-20-36(43)48/h31H,1-30H2,(H,40,44)(H,41,46)(H,42,45)(H,49,50)(H,52,53)/t31-/m0/s1 |
| InChI Key |
DVGUZQKRMQLDDD-HKBQPEDESA-N |
| Purity |
≥85% |
| Appearance |
White to light yellow solid |
| Applications/Corresponding APIs |
Semaglutide |
| EC Number |
815-717-1 |
| Isomeric SMILES |
C1CC(=O)N(C1=O)OC(=O)COCCOCCNC(=O)COCCOCCNC(=O)CC[C@@H](C(=O)O)NC(=O)CCCCCCCCCCCCCCCCC(=O)O |
| MDL Number |
MFCD32704903 |
| Storage Conditions |
Sealed, frozen (-20 °C ± 5 °C) |
It should be noted that our service is only used for research, not for clinical use.
