VAV1 degrader-3

VAV1 degrader-3

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VAV1 degrader-3

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Catalog Number	PR3050683387
CAS	3050683-38-7
Description	VAV1 degrader-3 is an orally active VAV1 molecular glue degrader (DC50: 7 nM). VAV1 degrader-3 reduces immune cell activation, immune cell proliferation and the production of various cytokines. VAV1 degrader-3 can be used for research of inflammatory or autoimmune disorder. VAV1 degrader-3 inhibits disease progression in experimntal autoimmune encephalomyelitis (EAE) mouse model, Collagen-induced arthritis (CIA) mouse model, etc.
Molecular Weight	392.83
Molecular Formula	C22H17ClN2O3
Canonical SMILES	ClC1=C(C2CCC(NC2=O)=O)C=CC=C1C3=CC=C(N4C(C=CC=C4)=O)C=C3
Shipping	Generally, shipped at room temperature in continental US; may vary elsewhere.

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