TMX-4100

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TMX-4100

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Catalog Number	PR2367619632
CAS	2367619-63-2
Structure
Description	TMX-4100 is a selective phosphodiesterase 6D (PDE6D) degrader. TMX-4100 shows a high degradation preference for PDE6D with the DC50 values less than 200 nM in MOLT4, Jurkat, and MM.1S cells. TMX-4100 can be used for the research of multiple myeloma.
IUPAC Name	3-(4-thiophen-3-yltriazol-1-yl)piperidine-2,6-dione
Molecular Weight	262.29
Molecular Formula	C11H10N4O2S
Canonical SMILES	O=C(C(N1N=NC(C2=CSC=C2)=C1)CC3)NC3=O
InChI	InChI=1S/C11H10N4O2S/c16-10-2-1-9(11(17)12-10)15-5-8(13-14-15)7-3-4-18-6-7/h3-6,9H,1-2H2,(H,12,16,17)
InChI Key	PGEUBQZQGXWTFO-UHFFFAOYSA-N
Purity	>98%
Appearance	White to off-white solid
Shipping	Generally, shipped at room temperature in continental US; may vary elsewhere.
Storage Conditions	Store at 4 °C

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