SJ6986
SJ6986
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SJ6986

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Catalog Number PR01268
Description SJ6986, a novel and potent GSPT1 degrader displaying selectivity over 9000 proteins, including the classical IMiD neosubstrates such as IKZF1. SJ6986 has very good oral bioavailability (F = 84% in mice).
Molecular Weight 497.4
Molecular Formula C20H14F3N3O7S
Canonical SMILES FC(F)(F)OC1=C(C=CC=C1)S(=O)(=O)NC1=CC2=C(C=C1)C(=O)N(C1CCC(=O)NC1=O)C2=O
Purity ≥95%
Solubility DMSO, DMF
Appearance White solid
Shipping Room temperature
Storage Conditions Refrigerated

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