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- Rizatriptan Benzoate
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Catalog Number | PR145202660 |
CAS | 145202-66-0 |
Structure | ![]() |
Description | Rizatriptan Benzoate is the benzoate salt form of rizatriptan, a member of the triptan class agents with anti-migraine property. Rizatriptan benzoate selectively binds to and activates serotonin (5-HT) 1B receptors expressed in intracranial arteries, and to 5-HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and central terminals in brain stem sensory nuclei. |
Synonyms | Maxalt; Maxalt-MLT; MK 462 |
IUPAC Name | benzoic acid;N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethanamine |
Molecular Weight | 391.5 |
Molecular Formula | C22H25N5O2 |
InChI | JPRXYLQNJJVCMZ-UHFFFAOYSA-N |
InChI Key | InChI=1S/C15H19N5.C7H6O2/c1-19(2)6-5-13-8-17-15-4-3-12(7-14(13)15)9-20-11-16-10-18-20;8-7(9)6-4-2-1-3-5-6/h3-4,7-8,10-11,17H,5-6,9H2,1-2H3;1-5H,(H,8,9) |
Documentation/Certification | CEP |
Isomeric SMILES | CN(C)CCC1=CNC2=C1C=C(C=C2)CN3C=NC=N3.C1=CC=C(C=C1)C(=O)O |
Therapeutic Category | Anti-Migraine |
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