PT-179
PT-179
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PT-179

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Catalog Number PR2924858251
CAS 2924858-25-1
Structure
Description PT-179 is able to specifically bind CRBN, form a ternary complex with a target protein fused to a zinc finger (ZF) degron, and mediate the degradation of the tagged protein.
IUPAC Name 2-(2,6-dioxopiperidin-3-yl)-5-morpholin-4-ylisoindole-1,3-dione
Molecular Weight 343.33
Molecular Formula C17H17N3O5
Canonical SMILES O=C1C2=CC=C(N3CCOCC3)C=C2C(N1C4C(NC(CC4)=O)=O)=O
InChI InChI=1S/C17H17N3O5/c21-14-4-3-13(15(22)18-14)20-16(23)11-2-1-10(9-12(11)17(20)24)19-5-7-25-8-6-19/h1-2,9,13H,3-8H2,(H,18,21,22)
InChI Key CCCSRHUSXCBFJZ-UHFFFAOYSA-N
Purity >99.5%
Appearance Light yellow to yellow solid
Shipping Generally, shipped at room temperature in continental US; may vary elsewhere.
Storage Conditions Store at 4 °C

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