Pizotifen Malate

Pizotifen Malate

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Pizotifen Malate

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Catalog Number	PR5189117
CAS	5189-11-7
Structure
Description	Pizotifen malate is a malate salt resulting from the reaction of equimolar amounts of pizotifen and malic acid. A sedating antihistamine with strong serotonin antagonist and weak antimuscarinic activity, it is used for the treatment of migraine and the prevention of headache attacks during cluster periods. It has a role as a histamine antagonist, a muscarinic antagonist and a serotonergic antagonist.
Synonyms	Pizotifen hydrogen malate
IUPAC Name	2-hydroxybutanedioic acid;1-methyl-4-(6-thiatricyclo[8.4.0.03,7]tetradeca-1(14),3(7),4,10,12-pentaen-2-ylidene)piperidine
Molecular Weight	429.5
Molecular Formula	C23H27NO5S
InChI	IWAWCPZVTXCFKD-UHFFFAOYSA-N
InChI Key	InChI=1S/C19H21NS.C4H6O5/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18;5-2(4(8)9)1-3(6)7/h2-5,10,13H,6-9,11-12H2,1H3;2,5H,1H2,(H,6,7)(H,8,9)
Isomeric SMILES	CN1CCC(=C2C3=C(CCC4=CC=CC=C42)SC=C3)CC1.C(C(C(=O)O)O)C(=O)O
Standard	In-house
Therapeutic Category	Ophthalmic Agents

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