LC3-mHTT-IN-AN1

Products

We are here to help in anything you need. Please use our online system or send an email to inquiry@alfa-chemistry.com.

LC3-mHTT-IN-AN1

Inquiry

Catalog Number	PR486443736
CAS	486443-73-6
Description	Compound AN1 reduces mHTT levels through autophagic degradation by interacting with both the autophagosome protein microtubule-associated protein 1A/1B light chain 3 (LC3)1 and mutant huntingtin protein (mHTT). AN1 reduces the levels of mHTT in an allele-selective manner in cultured Huntington disease (HD) mouse neurons.
Synonyms	LC3-mHTT-IN-1
IUPAC Name	(3Z)-5-bromo-3-[(3-bromo-4,5-dihydroxyphenyl)methylidene]-1H-indol-2-one
Molecular Weight	411.05
Molecular Formula	C15H9Br2NO3
Canonical SMILES	OC1=C(O)C(Br)=CC(\C=C2/C(=O)NC3=C2C=C(Br)C=C3)=C1
InChI	InChI=1S/C15H9Br2NO3/c16-8-1-2-12-9(6-8)10(15(21)18-12)3-7-4-11(17)14(20)13(19)5-7/h1-6,19-20H,(H,18,21)/b10-3-
InChI Key	GPKLWRHHVIBYEO-KMKOMSMNSA-N
Purity	≥95%
Solubility	DMSO, DMF
Appearance	White solid
Shipping	Room temperature
Storage Conditions	Refrigerated

It should be noted that our service is only used for research, not for clinical use.

We use cookies to understand how you use our site and to improve the overall user experience. This includes personalizing content and advertising. Read our Privacy Policy

Accept Cookies