Itraphylline
Itraphylline
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Itraphylline

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Catalog Number PR155270998
CAS 155270-99-8
Structure
Description Istradefylline is an adenosine receptor antagonist that is used as adjunctive therapy to levodopa/carbidopa in patients with Parkinson disease experiencing difficulty with "off" episodes when motor symptoms breakthrough on treatment.
Synonyms Nourianzl; KW6002
IUPAC Name 8-[(E)-2-(3,4-dimethoxyphenyl)ethenyl]-1,3-diethyl-7-methylpurine-2,6-dione
Molecular Weight 384.43
Molecular Formula C20H24N4O4
InChI IQVRBWUUXZMOPW-PKNBQFBNSA-N
InChI Key InChI=1S/C20H24N4O4/c1-6-23-18-17(19(25)24(7-2)20(23)26)22(3)16(21-18)11-9-13-8-10-14(27-4)15(12-13)28-5/h8-12H,6-7H2,1-5H3/b11-9+
Isomeric SMILES CCN1C2=C(C(=O)N(C1=O)CC)N(C(=N2)/C=C/C3=CC(=C(C=C3)OC)OC)C
Therapeutic Category Antiparkinson Agents

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