5-Hydroxythalidomide

5-Hydroxythalidomide

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5-Hydroxythalidomide

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Catalog Number	PR64567608
CAS	64567-60-8
Description	Thalidomide-5-OH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. It induces degradation of SALL4 (ZF2).
Synonyms	Thalidomide-5-OH
IUPAC Name	2-(2,6-dioxopiperidin-3-yl)-5-hydroxyisoindole-1,3-dione
Molecular Weight	274.23
Molecular Formula	C13H10N2O5
Canonical SMILES	OC1=CC2=C(C=C1)C(=O)N(C1CCC(=O)NC1=O)C2=O
InChI	InChI=1S/C13H10N2O5/c16-6-1-2-7-8(5-6)13(20)15(12(7)19)9-3-4-10(17)14-11(9)18/h1-2,5,9,16H,3-4H2,(H,14,17,18)
InChI Key	LJBQRRQTZUJWRC-UHFFFAOYSA-N
Purity	≥95%
Solubility	DMSO, DMF
Appearance	White solid
EC Number	965-879-3
Shipping	Room temperature
Storage Conditions	Refrigerated

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