dCeMM3
dCeMM3
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dCeMM3

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Catalog Number PR311787856
CAS 311787-85-6
Description dCeMM3 (Compound 3) is a glue degrader. dCeMM3 induces ubiquitination and degradation of cyclin K by prompting an interaction of CDK12-cyclin K with a CRL4B ligase complex.
Synonyms 2-((1H-benzo[d]imidazol-2-yl)thio)-N-(5-chloropyridin-2-yl)acetamide
IUPAC Name 2-(1H-benzimidazol-2-ylsulfanyl)-N-(5-chloropyridin-2-yl)acetamide
Molecular Weight 318.78
Molecular Formula C14H11ClN4OS
Canonical SMILES O=C(NC1=NC=C(Cl)C=C1)CSC2=NC3=CC=CC=C3N2
InChI InChI=1S/C14H11ClN4OS/c15-9-5-6-12(16-7-9)19-13(20)8-21-14-17-10-3-1-2-4-11(10)18-14/h1-7H,8H2,(H,17,18)(H,16,19,20)
InChI Key OOYJNUNOVRCHJZ-UHFFFAOYSA-N
Purity >98%
Appearance Light brown to brown solid
Shipping Generally, shipped at room temperature in continental US; may vary elsewhere.
Storage Conditions Store at 4 °C

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