CC-885
CC-885
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CC-885

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Catalog Number PR1010100078
CAS 1010100-07-8
Description CC-885 is a cereblon (CRBN) modulator with potent anti-tumour activity. CC-885 is also a known degrader of GSPT1, inhibiting protein translation.
IUPAC Name 1-(3-chloro-4-methylphenyl)-3-[[2-(2,6-dioxopiperidin-3-yl)-1-oxo-3H-isoindol-5-yl]methyl]urea
Molecular Weight 440.88
Molecular Formula C22H21ClN4O4
Canonical SMILES O=C(NCC1=CC2=C(C(N(C(CC3)C(NC3=O)=O)C2)=O)C=C1)NC4=CC=C(C)C(Cl)=C4
InChI InChI=1S/C22H21ClN4O4/c1-12-2-4-15(9-17(12)23)25-22(31)24-10-13-3-5-16-14(8-13)11-27(21(16)30)18-6-7-19(28)26-20(18)29/h2-5,8-9,18H,6-7,10-11H2,1H3,(H2,24,25,31)(H,26,28,29)
InChI Key DOEVCIHTTTYVCC-UHFFFAOYSA-N
Purity >99.5%
Appearance White to off-white solid
EC Number 991-036-4
Shipping Generally, shipped at room temperature in continental US; may vary elsewhere.
Storage Conditions Store at -20 °C

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