Pharmacology Scientist, Tumor Biology

As a leader in pharmacology research, Our company is seeking an accomplished scientist-level oncologist to join our translational science group in in vivo tumor biology. The successful candidate will join a dynamic team of scientists and play a leading role in the use of cancer models to evaluate new drug candidates, mechanisms, and targets.

Position Overview

The candidate will take part in preclinical drug research and development initiatives with a focus on tumors' intrinsic biology in relation to signal transduction, targeted treatments, and epigenetics. Additionally, the candidate will collaborate closely with partners to exploit and build state-of-the-art in vivo mouse and human cancer models for the assessment and characterization of both big and small compounds.

The candidate will provide technical and scientific expertise in in vivo pharmacology throughout the ORD to enable target identification, validation, prioritization, and effective drug discovery.

Key Responsibilities

• Plan, execute and analyze in vivo pharmacology studies.
• Characterize new in vivo mouse models, including homologous tumor and genetically engineered mouse models (GEMM), to investigate biological mechanisms and support the exploration of new therapies.
• Perform in vivo studies to assess and establish efficacy, PK/PD relationships, combination strategies, biomarker identification and analysis.
• Perform ancillary in vitro and ex vivo assays to characterize the effects of experimental drugs, which may include protein blotting, qPCR, scRNAseq, or other assays as needed.
• Document and interpret the quality of experimental results.
• Present results in a multidisciplinary team environment.
• Ensure appropriate use of animals in accordance with all regulatory requirements and internal standards.

Job Requirements

• Master's degree in biology/tumor biology/oncology or similar.
• Current knowledge of oncology research, therapeutic development, and discovery.
• Experience with animal models of human cancer. Understanding of blood/tissue collection and in vivo skills (IV, PO, SC, IP administration).
• Strong multitasking skills and ability to operate well in a team atmosphere that is diverse, fast-paced, and highly collaborative.
• Ability to contribute to a stimulating and intellectually challenging setting.
• The capacity to follow new discoveries in science or technology and use them in the lab.
• Excellent communication and presentation skills in English, both verbally and in writing.
• The capacity to incorporate biological ideas into experimental planning.

Join Us

Please fill out the form below if you believe you possess the qualities we are seeking. If you apply for a position that isn't open right now, we'll keep your resume on file and get in touch with you when it does. We do not accept calls from applications. We are eager to collaborate with you.